Fundamentals of Mass Spectrometry (MS) (1 of 7) - Electrospray Ionisation
What is Electrospray ionization?, Explain Electrospray ionization, Define Electrospray ionization
MS - Mass Spectrometry - Electron Ionization Animation
Electrospray ionization (ESI) is a technique used in mass spectrometry to produce ions using an electrospray in which a high voltage is applied to a liquid to create an aerosol. It is especially useful in producing ions from macromolecules because it overcomes the propensity of these molecules to fragment when ionized. ESI is different from other atmospheric pressure ionization processes since it may produce multiple-charged ions, effectively extending the mass range of the analyser to accommodate the kDa-MDa orders of magnitude observed in proteins and their associated polypeptide fragments.
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