Hematology | Erythropoiesis: Red Blood Cell Formation | Part 1
Gene Regulation and the Order of the Operon
Erythropoietin (EPO) in response to anemia
Anemia in Chronic Kidney Disease
Erythropoietin, also known as hematopoietin or hemopoietin, is a glycoprotein cytokine secreted by the kidney in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow. Low levels of EPO are constantly secreted sufficient to compensate for normal red blood cell turnover. Common causes of cellular hypoxia resulting in elevated levels of EPO include any anemia, and hypoxemia due to chronic lung disease.