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Geranylgeranyltransferase type 1


Medical vocabulary: What does Geranylgeranyl-Diphosphate Geranylgeranyltransferase mean


Gene Music using Protein Sequence of PDCD1LG2 "PROGRAMMED CELL DEATH 1 LIGAND 2"

Geranylgeranyltransferase type 1 or simply geranylgeranyltransferase is one of the three enzymes in the prenyltransferase group. In specific terms, Geranylgeranyltransferase adds a 20-carbon isoprenoid called a geranylgeranyl group to proteins bearing a CaaX motif: a four-amino acid sequence at the carboxyl terminal of a protein. Geranylgeranyltransferase inhibitors are being investigated as anti-cancer agents.
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    • Function 

    • Structure