Video encyclopedia

Giant-cell carcinoma of the lung


Large Cell Carcinoma of the Lung


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Small Cell vs Large Cell Carcinoma (Mnemonic)


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Giant-cell carcinoma of the lung (GCCL) is a rare histological form of large-cell lung carcinoma, a subtype of undifferentiated lung cancer, traditionally classified within the non-small-cell lung carcinomas (NSCLC).
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  • Classification 

  • Cytology 

  • Tissue architectural features 

  • Staining and immunohistochemistry 

  • Differential diagnosis 

  • Sites of metastasis 

  • Pathogenesis 

  • Combined/multiphasic tumors containing giant cells 

  • Imaging characteristics 

  • Positron emission tomography scanning 

  • Metabolic pathways 

  • Paraneoplastic syndromes 

  • Prognosis 

  • Epidemiology 

  • History