Mice "Tales"...the Knockout Mouse Production and Phenotyping Project
Adjourn - Colin Fletcher
Mouse genes could help decipher human disease
The International Knockout Mouse Consortium (IKMC) is a scientific endeavour to produce a collection of mouse embryonic stem cell lines that together lack every gene in the genome, and then to distribute the cells to scientific researchers to create knockout mice to study. Many of the targeted alleles are designed so that they can generate both complete and conditional gene knockout mice.
The IKMC was initiated on March 15, 2007 at a meeting in Brussels. By 2011, Nature reported that approximately 17,000 different genes have already been disabled by the consortium, "leaving only around 3,000 more to go".
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