"Izzo (H.O.V.A.)" is the first single released by Jay-Z from his sixth album The Blueprint. It is among his most popular singles. This was the second song released off The Blueprint, after the diss track "Takeover", but the lead single from it. The song reached #8 on the Billboard Hot 100 in the U.S. It was Jay-Z's first top 10 single as a lead artist.