Integral Membrane Proteins in the Plasma Membrane #biology #stem #educators
Integral and Peripheral Membrane Proteins (Part II)
Integral membrane proteins
308 Integral Membrane Proteins Have Stop Transfer Sequences
An integral membrane protein (IMP) is a type of membrane protein that is permanently attached to the biological membrane. All transmembrane proteins are IMPs, but not all IMPs are transmembrane proteins. IMPs comprise a significant fraction of the proteins encoded in an organism's genome. Proteins that cross the membrane are surrounded by annular lipids, which are defined as lipids that are in direct contact with a membrane protein. Such proteins can only be separated from the membranes by using detergents, nonpolar solvents, or sometimes denaturing agents.
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