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JDTic

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Synthesis of dibenzalacetone

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Preparation of Dibenzalacetone (Sunscreen) | Class 12 practical | aldol condensation

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Aldol Condensation to form Dibenzalacetone Part 1

JDTic is a selective, long-acting ("inactivating") antagonist of the κ-opioid receptor (KOR). JDTic is a 4-phenylpiperidine derivative, distantly related structurally to analgesics such as pethidine and ketobemidone, and more closely to the MOR antagonist alvimopan. In addition, it is structurally distinct from other KOR antagonists such as norbinaltorphimine.
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