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Phenytoin

8:14

Synthesis of Phenytoin and recrystallization

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PHENYTOIN Pharmacology : Antiepileptic Drugs

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Phenytoin Synthesis step 3: Condensation of urea and benzil

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Microwave Assisted Synthesis of Phenytoin

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Preparation of Phenytoin

Phenytoin (PHT), sold under the brand name Dilantin among others, is an anti-seizure medication. It is useful for the prevention of tonic-clonic seizures and partial seizures, but not absence seizures. The intravenous form is used for status epilepticus that does not improve with benzodiazepines. It may also be used for certain heart arrhythmias or neuropathic pain. It can be taken intravenously or by mouth. The intravenous form generally begins working within 30 minutes and is effective for 24 hours. Blood levels can be measured to determine the proper dose.
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