Nischayananda was a direct monastic disciple of Vivekananda. He, together with Kalyanananda was responsible for setting up and running the Ramakrishna Mission Sevashrama, Kankhal. He was inspired by Vivekananda's philosophy of serving man as God and dedicated his life to serve poor and downtrodden in the remote areas where no healthcare facility existed. He worked in military service before joining the Ramakrishna Order as a direct monastic disciple of Vivekananda. He met Vivekananda in Madras and decided to become his disciple. After Vivekananda's death, he went for pilgrimage and by chance came to Haridwar where he met his brother disciple Kalyanananda and joined him in carrying out the works of Ramakrishna Mission Sevashrama Kankhal.