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Gene Regulation and the Order of the Operon




Operons and gene regulation in bacteria


The Lac operon | Regulation of gene expression


Lac Operon

In genetics, an operon is a functioning unit of DNA containing a cluster of genes under the control of a single promoter. The genes are transcribed together into an mRNA strand and either translated together in the cytoplasm, or undergo splicing to create monocistronic mRNAs that are translated separately, i.e. several strands of mRNA that each encode a single gene product. The result of this is that the genes contained in the operon are either expressed together or not at all. Several genes must be co-transcribed to define an operon.
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  • History 

  • Overview 

  • As a unit of transcription 

  • Operons versus clustering of prokaryotic genes 

  • General structure 

  • Regulation 

  • The ''lac'' operon 

  • The ''trp'' operon 

  • Predicting the number and organization of operons