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Video encyclopedia

TPX2

Targeting protein for Xklp2 is a protein that in humans is encoded by the TPX2 gene.
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  • Key domains of TPX2 

  • Role in microtubule assembly 

  • Activation and reciprocation through Aurora A kinase 

  • Role in cleavage arrest and interaction with Eg5 

  • Regulation of TPX2 in the cell cycle 

  • Role in the nucleus 

  • Relevance in cancer