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TRNA-dihydrouridine16/17 synthase

TRNA-dihydrouridine16/17 synthase (NAD(P)+) (EC 1.3.1.88, Dus1p, tRNA-dihydrouridine synthase 1) is an enzyme with systematic name tRNA-5,6-dihydrouracil16/17:NAD(P)+ oxidoreductase. This enzyme catalyses the following chemical reaction(1) 5,6-dihydrouracil16 in tRNA + NAD(P)+ uracil16 in tRNA + NAD(P)H + H+ (2) 5,6-dihydrouracil17 in tRNA + NAD(P)+ uracil17 in tRNA + NAD(P)H + H+