Mechanism of action and resistance mechanisms for beta lactam antibiotics
Resistance to Beta-lactam Antibiotics in Bacteria
The Beta-lactam Antibiotic Crisis
Penicillin Mechanism of Action animation video
Brandl's Basics: Mechanism of action of beta-lactam antibiotics
Β-lactam antibiotics are a class of broad-spectrum antibiotics, consisting of all antibiotic agents that contain a beta-lactam ring in their molecular structures. This includes penicillin derivatives (penams), cephalosporins (cephems), monobactams, and carbapenems. Most β-lactam antibiotics work by inhibiting cell wall biosynthesis in the bacterial organism and are the most widely used group of antibiotics. Until 2003, when measured by sales, more than half of all commercially available antibiotics in use were β-lactam compounds.