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TXN

2:28

64: Thioredoxin

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Gene Music using Protein Sequence of TMX3 "THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 3"

1:12

Gene Music using Protein Sequence of TMX1 "THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 1"

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Gene Music using Protein Sequence of TXNIP "THIOREDOXIN INTERACTING PROTEIN"

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Gene Music using Protein Sequence of TMX4 "THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 4"

Thioredoxin is a class of small redox proteins known to be present in all organisms. It plays a role in many important biological processes, including redox signaling. In humans, thioredoxins are encoded by TXN and TXN2 genes. Loss-of-function mutation of either of the two human thioredoxin genes is lethal at the four-cell stage of the developing embryo. Although not entirely understood, thioredoxin plays a central role in humans and is increasingly linked to medicine through their response to reactive oxygen species (ROS). In plants, thioredoxins regulate a spectrum of critical functions, ranging from photosynthesis to growth, flowering and the development and germination of seeds. They have also recently been found to play a role in cell-to-cell communication.
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  • Function 

  • Mechanism of action 

  • Interactions 

  • Effect on cardiac hypertrophy