Neotoma leucodon is a species of rodent in the family Cricetidae. Although originally named from San Luis Potosí, Mexico, as a species by Merriam, the white-toothed woodrat was long considered to be a synonym of the white-throated woodrat. Molecular data, however, indicate the populations east of the Rio Grande in New Mexico and Trans-Pecos Texas represent a different species than morphologically similar populations west of the river.