Mark B. Pochapin, MD, FACG on Elevated Gastrin Levels and Atrophic Gastritis
What is ATROPHIC GASTRITIS? What does ATROPHIC GASTRITIS mean? ATROPHIC GASTRITIS meaning
1191: Atrophic Gastritis or Cobalamin Deficiency
Chronic atrophic gastritis
Atrophic gastritis (also known as Type A or Type B Gastritis more specifically) is a process of chronic inflammation of the stomach mucous membrane (mucosa), leading to loss of gastric glandular cells and their eventual replacement by intestinal and fibrous tissues. As a result, the stomach's secretion of essential substances such as hydrochloric acid, pepsin, and intrinsic factor is impaired, leading to digestive problems. The most common are vitamin B12 deficiency which results in a megaloblastic anemia and malabsorption of iron, leading to iron deficiency anaemia. It can be caused by persistent infection with Helicobacter pylori, or can be autoimmune in origin. Those with the autoimmune version of atrophic gastritis are statistically more likely to develop gastric carcinoma, Hashimoto's thyroiditis, and achlorhydria.