Osbaldeston is a surname. Notable people with the surname include:Edward Osbaldeston,, Catholic martyr
George Osbaldeston, (1786–1866), cricketer
Gordon Osbaldeston,, former Canadian civil servant
Lambert Osbaldeston, (1594–1659), headmaster of Westminster School
Richard Osbaldeston, (1691–1764), Bishop of London
Tess Anne Osbaldeston, translator of Dioscorides' De Materia Medica
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