Ptahhotep Desher was an Ancient Egyptian official at the end of the Fifth Dynasty, most likely in office under kings Menkauhor Kaiu and Djedkare Isesi. His main function was that of a vizier. This was the most important office in Ancient Egypt, second only to the king. Ptahhotep also held other titles, such as overseer of the six great houses, overseer of the scribes of the royal documents and overseer of all royal works. These are all important functions, often held by a vizier.