Puinawai Natural Reserve is the second-largest national park in Colombia. This protected area occupies 10,925 square kilometres (4,218 sq mi) of the Amazon Region of Colombia, roughly 15% of the Guainía Department. The Reserve was created in September 1989 and coincides with three important indigenous territories that were also formed at the same time. Several rivers cross the Natural Reserve belonging to the Amazon River basin: The Cuyari, Isana and Guainía River. And belonging to the Orinoco River basin, the Inírida River. The Natural Reserve lies between altitude of 200 to 380 metres above sea level and its climate is hot and humid with little seasonal variations throughout the year.