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BK channel

3:51

Pagkagising sa Umaga : Ang Mga Ibon Na Lumilipad | Pinoy BK Channel🇵🇭 | TAGALOG CHRISTIAN SONG

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Ang Mga Ibon na Lumilipad 2017 | Pinoy BK Channel🇵🇭 | TAGALOG CHRISTIAN SONGS

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Pagibig Tulad ng Batis | Pinoy BK Channel🇵🇭 | TAGALOG FOR KIDS (AWITING PAMBATA)

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BATIBOT THEME SONG | Pinoy BK Channel🇵🇭 | TAGALOG FOR KIDS (AWITING PAMBATA)

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Beybi Pating (Baby Shark Tagalog) | Pinoy BK Channel🇵🇭 | SONGS FOR KIDS (AWITING PAMBATA)

BK channels (Big Potassium), also known as Maxi-K, slo1, or Kcal.1, are voltage-gated potassium channels that conduct large amounts of potassium ions (K+) across the cell membrane, hence their name, Big Potassium. These channels can be activated (opened) by either electrical means, or by increasing calcium concentrations in the cell. BK channels help regulate physiological processes, such as circadian behavioral rhythms and neuronal excitability. BK channels are also involved in many processes in the body, as it is a ubiquitous channel. They have a tetrameric structure that is composed of a transmembrane domain, voltage sensing domain, potassium channel domain, and a cytoplasmic C-terminal domain, with many X-ray structures for reference. Their function is to repolarize the membrane potential by allowing for potassium to flow outward, in response to a depolarization or increase in calcium levels.
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    • Structure 

    • Regulation 

    • Activation mechanism 

    • Effects on the neuron, organ, body as a whole 

    • Pharmacology