BRCA1
6:41
A guide to BRCA1 and BRCA2 gene mutations in hereditary breast and ovarian cancer
17:32
BRCA mutation
3:52
Understanding BRCA Mutations and Risk
8:25
The Role of BRCA1 in Cancer
3:12
BRCA Genes and Breast Cancer
BRCA1 and BRCA1 are a human gene and its protein product, respectively. The official symbol and the official name are maintained by the HGNC. Orthologs, styled Brca1 and Brca1, are common in other mammalian species. BRCA1 is a human tumor suppressor gene, found in all humans; its protein, also called by the synonym breast cancer type 1 susceptibility protein, is responsible for repairing DNA.
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Discovery
Gene location
Protein structure
Function and mechanism
Mutations and cancer risk
Low expression of ''BRCA1'' in breast and ovarian cancers
Germ line mutations and founder effect
Patents, enforcement, litigation, and controversy
Interactions