SYNTHESIS OF BARBITAL (BARBITONE) SODIUM | MEDICINAL CHEMISTRY | GPAT-2020 | B.PHARM-4TH SEM
Dimethyl barbituric acid synthesis
Synthesis of Barbital or Barbitone
SAR Structure Activity Relationship of Barbiturate || L-4 Unit-4 Medicinal Chemistry -I
Barbital, marketed under the brand names Veronal for the pure acid and Medinal for the sodium salt, was the first commercially available barbiturate. It was used as a sleeping aid (hypnotic) from 1903 until the mid-1950s. The chemical names for barbital are diethylmalonyl urea or diethylbarbituric acid; hence, the sodium salt is known also as sodium diethylbarbiturate.