SYNTHESIS OF BARBITAL (BARBITONE) SODIUM | MEDICINAL CHEMISTRY | GPAT-2020 | B.PHARM-4TH SEM
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Dimethyl barbituric acid synthesis
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Synthesis of Barbital or Barbitone
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SAR Structure Activity Relationship of Barbiturate || L-4 Unit-4 Medicinal Chemistry -I
Barbital, marketed under the brand names Veronal for the pure acid and Medinal for the sodium salt, was the first commercially available barbiturate. It was used as a sleeping aid (hypnotic) from 1903 until the mid-1950s. The chemical names for barbital are diethylmalonyl urea or diethylbarbituric acid; hence, the sodium salt is known also as sodium diethylbarbiturate.