Pharmacology of Barbiturates - Usmle , Fmge , Neet pg : Dr Rajesh gubba
Structural Activity Relationship (SAR) of Barbiturates
Barbiturates and Benzodiazepines
Toxicology (Part-11) Barbiturate Poisoning = Symptoms and Treatment (HINDI)
Sedatives and Hypnotics (complete) SAR | Benzodiazepines | Barbiturates | P-1 U-4 Medicinal Chem. 1
A barbiturate is a drug that acts as a central nervous system depressant, and can therefore produce a wide spectrum of effects, from mild sedation to death. They are effective as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological addiction potential. They have largely been replaced by benzodiazepines in routine medical practice, particularly in the treatment of anxiety and insomnia, due to the significantly lower risk of addiction and overdose and the lack of an antidote for barbiturate overdose. Despite this, barbiturates are still in use for various purposes: in general anesthesia, epilepsy, treatment of acute migraines or cluster headaches, euthanasia, capital punishment, and assisted suicide.