logo

Video encyclopedia

Caspofungin

26:08

Discovery of natural products that potentiate the activity of current antifungal drugs

6:37

Pharmacology – ANTIFUNGAL DRUGS (MADE EASY)

8:32

Caspofungin

3:41

Mechanism of action of amphotericin B ketoconazole Caspofungin antifungal drugs

10:06

How To Administer IV Medication Using Gravity Infusion | Sutter Infusion Pharmacy Services

Caspofungin (INN) is a lipopeptide antifungal drug from Merck & Co., Inc. discovered by James Balkovec, Regina Black and Frances A. Bouffard. It is a member of a new class of antifungals termed the echinocandins. It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin was the first inhibitor of fungal (1→3)-β-D-glucan synthesis to be approved by the United States Food and Drug Administration. Caspofungin is administered intravenously.
  • Spectrum of Activity 

  • Indications 

  • Warnings 

  • Side effects 

  • Semisynthesis