Discovery of natural products that potentiate the activity of current antifungal drugs
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Pharmacology – ANTIFUNGAL DRUGS (MADE EASY)
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Caspofungin
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Mechanism of action of amphotericin B ketoconazole Caspofungin antifungal drugs
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How To Administer IV Medication Using Gravity Infusion | Sutter Infusion Pharmacy Services
Caspofungin (INN) is a lipopeptide antifungal drug from Merck & Co., Inc. discovered by James Balkovec, Regina Black and Frances A. Bouffard. It is a member of a new class of antifungals termed the echinocandins. It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin was the first inhibitor of fungal (1→3)-β-D-glucan synthesis to be approved by the United States Food and Drug Administration.
Caspofungin is administered intravenously.