Princess Friederike of Schleswig-Holstein-Sonderburg-Glücksburg was a daughter of Friedrich Wilhelm, Duke of Schleswig-Holstein-Sonderburg-Glücksburg and Princess Louise Caroline of Hesse-Kassel and an elder sister of Christian IX of Denmark. Friederike became the Duchess of Anhalt-Bernburg upon her marriage to Alexander Karl, Duke of Anhalt-Bernburg, the last Duke of Anhalt-Bernburg. She served as Regent of the Duchy from 1855 to 1863.