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P53

3:01

700 for Science Presents p53 Therapeutics: Role of p53 gene in cancer

2:12

TP53-inducible glycolysis and apoptosis regulator - Video Learning - WizScience.com

2:04

Part two of Genetics of Cancer and P53

3:25

LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control

0:16

[Wikipedia] P53 regulation associated lncRNA

Tumor protein p53, also known as p53, cellular tumor antigen p53, phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice). This homolog is crucial in multicellular organisms, where it prevents cancer formation, thus, functions as a tumor suppressor. As such, p53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation. Hence TP53 is classified as a tumor suppressor gene.
  • Gene 

  • Structure 

  • Function 

  • Regulation 

  • Role in disease 

  • Experimental analysis of p53 mutations 

  • Discovery 

  • Isoforms 

  • Interactions