logo

Video encyclopedia

Acyl carrier protein

5:09

Fatty Acid Synthesis

5:35

Carrier Proteins

12:09

Fatty Acid Synthesis Pathway: Overview, Enzymes and Regulation

5:30

Acyl Carrier Protein Shake

7:34

Fatty Acid Synthesis (Part 4 of 12) - Fatty Acid Synthase Complex

The acyl carrier protein (ACP) is an important component in both fatty acid and polyketide biosynthesis with the growing chain bound during synthesis as a thiol ester at the distal thiol of a 4'-phosphopantetheine moiety. The protein is expressed in the inactive apo form and the 4'-phosphopantetheine moiety must be post-translationally attached to a conserved serine residue on the ACP by the action of holo-acyl carrier protein synthase (ACPS), a 4'-phosphopantetheinyl transferase.
  • General