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C-reactive protein

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Explanation of 5' and 3', C terminus, and N terminus | MIT 7.01SC Fundamentals of Biology

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RNA Splicing Animation: There are 7 steps more details in text below.

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C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, whose levels rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells. Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells in order to activate the complement system via C1q.
  • History 

  • Nomenclature 

  • Genetics and structure 

  • Function 

  • Serum levels 

  • Clinical significance