Anthrax Lethal Toxin 3D model from X-ray, Rate My Science
Anthrax toxin lethal factor domain 3 is highly mobile and responsive to ligand binding
Anthrax lethal factor endopeptidase is an enzyme that catalyzes the hydrolysis of mitogen-activated protein kinase kinases. This enzyme is a component of the lethal factor produced by the bacterium Bacillus anthracis. The preferred cleavage site can be denoted by BBBBxHxH, in which B denotes a basic amino acid Arg or Lys, H denotes a hydrophobic amino acid, and x is any amino acid.