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Science, Health

Alexander Fleming

Sir Alexander Fleming was a Scottish physician, microbiologist, and pharmacologist. His best-known discoveries are the enzyme lysozyme in 1923 and the world's first antibiotic substance benzylpenicillin from the mould Penicillium notatum in 1928, for which he shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Ernst Boris Chain. He wrote many articles on bacteriology, immunology, and chemotherapy.

Science, Health

Alexander Shulgin

Alexander Theodore Shulgin was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author. He is credited with introducing MDMA to psychologists in the late 1970s for psychopharmaceutical use and for the discovery, synthesis and personal bioassay of over 230 psychoactive compounds for their psychedelic and entactogenic potential.

Science, Health

Frances Oldham Kelsey

Frances Kathleen Oldham Kelsey, CM was a Canadian-American pharmacologist and physician. As a reviewer for the U.S. Food and Drug Administration (FDA), she refused to authorize thalidomide for market because she had concerns about the drug's safety. Her concerns proved to be justified when it was shown that thalidomide caused serious birth defects. Kelsey's career intersected with the passage of laws strengthening FDA oversight of pharmaceuticals. Kelsey was the second woman to be awarded the President's Award for Distinguished Federal Civilian Service by President John F. Kennedy.

Science, Health

Gertrude B. Elion

Gertrude Belle Elion was an American biochemist and pharmacologist, who shared the 1988 Nobel Prize in Physiology or Medicine with George H. Hitchings and Sir James Black. Working alone as well as with Hitchings and Black, Elion developed a multitude of new drugs, using innovative research methods that would later lead to the development of the AIDS drug AZT. She developed the first immunosuppressive drug, azathioprine, used for organ transplants. She also developed the first successful antiviral drug, acyclovir (ACV), for the treatment of Herpes infection.

Art, Science, Health

Pedanius Dioscorides

Pedanius Dioscorides was a Greek physician, pharmacologist, botanist, and author of De Materia Medica —a 5-volume Greek encyclopedia about herbal medicine and related medicinal substances, that was widely read for more than 1,500 years. He was employed as a medic in the Roman army.

Science, Health

Ferid Murad

Ferid Murad is a physician and pharmacologist, and a co-winner of the 1998 Nobel Prize in Physiology or Medicine.

Science, Health

Louis Ignarro

Louis J. Ignarro is an American pharmacologist. For demonstrating the signaling properties of nitric oxide, he was co-recipient of the 1998 Nobel Prize in Physiology or Medicine with Robert F. Furchgott and Ferid Murad.

Technology and industry, Science, Health

James Black (pharmacologist)

Sir James Whyte Black was a Scottish physician and pharmacologist. Black established a Veterinary Physiology department at the University of Glasgow, where he became interested in the effects of adrenaline on the human heart. He went to work for ICI Pharmaceuticals in 1958 and, while there, developed propranolol, a beta blocker used for the treatment of heart disease. Black was also responsible for the development of cimetidine, an H2 receptor antagonist, a drug used to treat stomach ulcers. He was awarded the Nobel Prize for Medicine in 1988 for work leading to the development of propranolol and cimetidine.

Science, Health

Otto Loewi

Otto Loewi was a German-born pharmacologist and psychobiologist who discovered the role of acetylcholine as an endogenous neurotransmitter. For his discovery he was awarded the Nobel Prize in Physiology or Medicine in 1936, which he shared with Sir Henry Dale, who was a lifelong friend who helped to inspire the neurotransmitter experiment. Loewi met Dale in 1902 when spending some months in Ernest Starling's laboratory at University College, London.

Science, Health

Salvador Moncada

Sir Salvador Moncada, FRS, FRCP, FMedSci is a Honduran-British pharmacologist and professor. He is currently Research Domain Director for Cancer at the University of Manchester.

Science, Health

David E. Nichols

David Earl Nichols is an American pharmacologist and medicinal chemist. Previously the Robert C. and Charlotte P. Anderson Distinguished Chair in Pharmacology at Purdue University, Nichols has worked in the field of psychoactive drugs since 1969. While still a graduate student, he patented the method that is used to make the optical isomers of hallucinogenic amphetamines. His contributions include the synthesis and reporting of escaline, LSZ, 6-APB, 2C-I-NBOMe and other NBOMe variants, and several others, as well as the coining of the term "entactogen".

Science, Health

Alfred G. Gilman

Alfred Goodman Gilman was an American pharmacologist and biochemist. He and Martin Rodbell shared the 1994 Nobel Prize in Physiology or Medicine "for their discovery of G-proteins and the role of these proteins in signal transduction in cells."

Science, Health

Ulf von Euler

Ulf Svante von Euler was a Swedish physiologist and pharmacologist. He shared the Nobel Prize in Physiology or Medicine in 1970 for his work on neurotransmitters.

Science, Health

Daniel Bovet

Daniel Bovet was a Swiss-born Italian pharmacologist who won the 1957 Nobel Prize in Physiology or Medicine for his discovery of drugs that block the actions of specific neurotransmitters. He is best known for his discovery in 1937 of antihistamines, which block the neurotransmitter histamine and are used in allergy medication. His other research included work on chemotherapy, sulfa drugs, the sympathetic nervous system, the pharmacology of curare, and other neuropharmacological interests.

Science, Health

John Vane

Sir John Robert Vane FRS was an English pharmacologist who was instrumental in the understanding of how aspirin produces pain-relief and anti-inflammatory effects and his work led to new treatments for heart and blood vessel disease and introduction of ACE inhibitors. He was awarded the Nobel Prize in Physiology or Medicine in 1982 along with Sune Bergström and Bengt Samuelsson for "their discoveries concerning prostaglandins and related biologically active substances".